Severe human bone infection due to methicillin-resistant Staphylococcus aureus carrying the novel mecC variant.
نویسندگان
چکیده
CHU Limoges, Laboratoire de Bactériologie-Virologie-Hygiène, 2 Avenue Martin Luther King, Limoges F-87042, France; INSERM, U1092, Limoges F-87000, France; Université de Limoges, UMRS1092, Faculté de Médecine, 2 rue du Dr Marcland, Limoges F-87025, France; Hospices Civils de Lyon, Centre National de Référence des Staphylocoques, 59 Boulevard Pinel, Bron cedex F-69677, France; Centre International de Recherche en Infectiologie (CIRI)-Inserm U1111, CNRS UMR5308, UCBL, ENSL, Equipe ‘Pathogénèse des infections à staphylocoques’, 7 rue Guillaume Paradin, Lyon F-69317, France; CHU Limoges, Service de Réanimation Polyvalente, 2 Avenue Martin Luther King, Limoges F-87042, France
منابع مشابه
Epidemiology of methicillin-resistant Staphylococcus aureus carrying the novel mecC gene in Denmark corroborates a zoonotic reservoir with transmission to humans.
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcare-associated (HA), community-associated (CA) and livestock-associated (LA) infections. Recently, the discovery of human and bovine MRSA isolates carrying a new mecA gene homologue, mecA(LGA251) (now designated mecC), has caused concern because they are not detected by conventional, confirmatory tests for MRSA. Very ...
متن کاملReport of mecC-carrying MRSA in domestic swine
OBJECTIVES We unexpectedly identified MRSA isolates carrying mecC (mecC-MRSA) from a Danish swine farm located in eastern Zealand. The objective of the present study was to investigate the origin of these isolates and their genetic relatedness to other mecC-MRSA isolates from Zealand. METHODS WGS was used to infer the phylogenetic relationship between 19 identified mecC-MRSA isolates from the...
متن کاملMRSA Harboring mecA Variant Gene mecC, France
We describe human cases and clustered animal cases of mecA(LGA251)-positive methicillin-resistant Staphylococcus aureus in France. Our report confirms that this new variant has a large distribution in Europe. It may represent a public health threat because phenotypic and genotypic tests seem unable to detect this new resistance mechanism.
متن کاملMethicillin-resistant Staphylococcus aureus containing mecC in Swedish dairy cows
BACKGROUND Hitherto, methicillin-resistant Staphylococcus aureus (MRSA) has not been detected in Swedish cattle. However, due to the report of mecC, a novel homologue to the mecA gene, there was reason to re-evaluate susceptibility results from strain collections of Staphylococcus aureus and test suspected isolates for the presence of mecC. FINDINGS Bovine isolates of S. aureus with elevated ...
متن کاملDetection of methicillin-resistant Staphylococcus aureus (MRSA) carrying the mecC gene in wild small mammals in Spain.
OBJECTIVES To determine the rate of Staphylococcus aureus faecal carriage in 101 wild small mammals in Spain and to characterize the isolates obtained. METHODS Faecal samples were seeded on mannitol salt agar and ORSAB plates. The presence of the resistance genes mecA, mecC and blaZ and the new blaZ allotype associated with staphylococcal cassette chromosome mec (SCCmec) XI (blaZ-SCCmecXI) wa...
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ورودعنوان ژورنال:
- The Journal of antimicrobial chemotherapy
دوره 68 12 شماره
صفحات -
تاریخ انتشار 2013